RNA Details
Disease Name
pulmonary hypertension
Tissue
lung
RNA Symbol
Cdkn1a
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Immunohistochemistry; qRT-PCR; etc.
Target
P21
Pathway
NA
PubMed ID
Title
Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension
Year
2012
Function
MiR-17 antagomir A-17 improves heart and lung function in experimental PH by interfering with lung vascular and right ventricular remodeling. The beneficial effects may be related to the up-regulation of p21.